Politically speaking, the absolute easiest call is for national Democrats to pressure Al Franken to resign. He’d be replaced by someone appointed by the Democratic governor of Minnesota, who would then have at least as good a shot as Franken at getting elected in his own right. If Franken resisted said calls to resign, the Senate would face the possibility of expelling him -- which, in light of the horny skeletons undoubtedly frolicking in both their closets, would be a problem for both parties. Meanwhile, the Democratic establishment could echo anti-Roy Moore Republicans and say, “Oh all right, we've made our objections clear, we leave it up to the voters of his state,” who would then almost certainly choose Franken or someone ideologically akin to Franken.
Yes "almost": Though it is far from unimaginable for Minnesota to elect a Republican, it is more so today than it was in 2016, when Minnesota was the rare Rust Belt state that went for Hillary Clinton. But even if the seat were somehow to go to a Minnesota-shade Republican Democrats would gain a crucial line of attack in the sexual-assault wars: "Hey, GOP, go ahead and harp on Bill Clinton. Today, we reject our gropers. You protect your child molesters."
Morally and practically, though, the question remains: If everyone, in and out of politics, who has ever, at any point, done what Franken is currently known to have done were to be found out and fired….would that be a good thing or a bad thing? I’m honestly not sure. But now that two out of three network morning-news hosts, numerous titans of Hollywood and Silicon Valley, a significant swath of the Catholic clergy, and a whole roster of big names in both political parties including at least one president each have been credibly accused of much worse, it would certainly be a shattering, an unraveling, a societal convulsion to the core.